Buy Hydroxychloroquine, also known as chloroquine, is a medication with a mechanism of action that makes it useful in the treatment of both malaria and autoimmune diseases. Here's how it works in the body:
Malaria:
Malaria:
- In the context of malaria, hydroxychloroquine is used as an antimalarial drug. It works by interfering with the life cycle of the Plasmodium parasites responsible for malaria.
- Red Blood Cell Invasion: Malaria parasites, specifically Plasmodium falciparum, invade red blood cells, where they multiply and cause the characteristic symptoms of the disease.
- Hemozoin Formation: These parasites digest hemoglobin, releasing a toxic product called heme. To avoid toxicity, the parasites convert heme into a crystalline substance called hemozoin.
- Interference with Hemozoin Formation: Hydroxychloroquine accumulates in the acidic food vacuoles of the parasite within the red blood cells. It interferes with the formation of hemozoin, preventing the detoxification of heme. This leads to an accumulation of toxic heme within the parasite, ultimately killing it.
- Anti-Inflammatory Effects: Hydroxychloroquine also exhibits anti-inflammatory effects, which can help reduce the inflammatory response associated with malaria infection.